Arterial Blood Gas Tensions After Resuscitation From Out-of-Hospital Cardiac Arrest: Associations With Long-Term Neurologic Outcome

Vaahersalo, Jukka MD; Bendel, Stepani MD, PhD; Reinikainen, Matti MD, PhD; Kurola, Jouni MD, PhD; Tiainen, Marjaana MD, PhD; Raj, Rahul BM; Pettilä, Ville MD, PhD; Varpula, Tero MD, PhD; Skrifvars, Markus B. MD, PhD, FCICM

Critical Care Medicine:

June 2014 - Volume 42 - Issue 6 - p 1463-1470  

This study included out-of-hospital cardiac arrest patients treated in ICUs in Finland between March 2010 and February 2011.

The cerebral performance category at 12 months was used as primary endpoint. 
A total of 409 patients with arterial blood gases analyzed at least once and with a complete set of resuscitation data were included.

In this multicenter study, hypercapnia was associated with good 12-month outcome in patients resuscitated from out-of-hospital cardiac arrest. 

They were unable to verify any harm from hyperoxia exposure.