Thursday, June 26, 2014
The use of a nasogastric tube to facilitate nasotracheal intubation: a randomised controlled trial
C.-W. Lim,S.-W. Min et al
During nasotracheal intubation, the tracheal tube passes through either the upper or lower pathway in the nasal cavity, and it has been reported to be safer that the tracheal tube passes though the lower pathway, just below the inferior turbinate. We evaluated the use of a nasogastric tube as a guide to facilitate tracheal tube passage through the lower pathway, compared with the ‘conventional’ technique (blind insertion of the tracheal tube into the nasal cavity). A total of 60 adult patients undergoing oral and maxillofacial surgery were included in the study. In 20 out of 30 patients (66.7%) with the nasogastric tube-guided technique, the tracheal tube passed through the lower pathway, compared with 8 out of 30 patients (26.7%) with the ‘conventional’ technique (p = 0.004). Use of the nasogastric tube-guided technique reduced the incidence and severity of epistaxis (p = 0.027), improved navigability (p = 0.034) and required fewer manipulations (p = 0.001) than the ‘conventional’ technique
Sunday, June 22, 2014
Increased risk of acute kidney injury associated with higher infusion rate of mannitol in patients with intracranial hemorrhage
Clinical article
Min Young Kim ,MD et al
Journal of Neurosurgery
Jun 2014 / Vol. 120 / No. 6
/
Pages 1340-1348
The objectives of this study were to assess the impact of mannitol on
the incidence and severity of acute kidney injury (AKI) and to identify risk factors and
outcome for AKI in patients with intracranial hemorrhage (ICH).
The authors retrospectively evaluated 153 adult patients who received
mannitol infusion after ICH between January 2005 and December 2009 in
the neurosurgical intensive care unit.
The overall incidence of AKI among study participants was 10.5%
(n =
16).
Acute kidney injury occurred more frequently in patients who
received mannitol infusion at a rate ≥ 1.34 g/kg/day than it did in
patients who received mannitol infusion at a rate < 1.34 g/kg/day.
A
higher mannitol infusion rate was associated with more severe AKI.
Independent risk factors for AKI were mannitol infusion rate ≥ 1.34
g/kg/day, age ≥ 70 years, diastolic blood pressure (DBP) ≥ 110 mm Hg,
and glomerular filtration rate < 60 ml/min/1.73 m2
Journal of Neurosurgery
Jun 2014 / Vol. 120 / No. 6 / Pages 1340-1348
The objectives of this study were to assess the impact of mannitol on
the incidence and severity of acute kidney injury (AKI) and to identify risk factors and
outcome for AKI in patients with intracranial hemorrhage (ICH).
The authors retrospectively evaluated 153 adult patients who received
mannitol infusion after ICH between January 2005 and December 2009 in
the neurosurgical intensive care unit.
The overall incidence of AKI among study participants was 10.5%
(n =
16).
Acute kidney injury occurred more frequently in patients who
received mannitol infusion at a rate ≥ 1.34 g/kg/day than it did in
patients who received mannitol infusion at a rate < 1.34 g/kg/day.
A
higher mannitol infusion rate was associated with more severe AKI.
Independent risk factors for AKI were mannitol infusion rate ≥ 1.34
g/kg/day, age ≥ 70 years, diastolic blood pressure (DBP) ≥ 110 mm Hg,
and glomerular filtration rate < 60 ml/min/1.73 m2
Low intraoperative tidal volume ventilation with minimal PEEP is associated with increased mortality
P. J. McCormick et al .
BJA,Volume 113,Issue 1 Pp 07-108,July 2014
Anaesthetists have traditionally ventilated patients' lungs with tidal volumes (TVs) between 10 and 15 ml kg−1
of ideal body weight (IBW), without the use of PEEP. Over the past
decade, influenced by the results of the Acute Respiratory
Distress Syndrome Network trial, many
anaesthetists have begun using lower TVs during surgery. It is unclear
whether the benefits
of low TV ventilation can be extended into the
perioperative period.
Methods We reviewed the records of 29 343 patients who underwent general anaesthesia with mechanical ventilation between January
1, 2008 and December 31, 2011. We calculated TV kg−1 IBW, PEEP, peak inspiratory pressure (PIP), and dynamic compliance. Cox regression analysis with propensity score matching
was performed to examine the association between TV and 30-day mortality.
Results Median TV was 8.6 [7.7–9.6] ml kg−1 IBW with minimal PEEP [4.0 (2.2–5.0) cm H2O]. A significant reduction in TV occurred over the study period, from 9 ml kg−1 IBW in 2008 to 8.3 ml kg−1 IBW in 2011 (P=0.01). Low TV 6–8 ml kg−1 IBW was associated with a significant increase in 30-day mortality vs TV 8–10 ml kg−1 IBW: hazard ratio (HR) 1.6 [95% confidence interval (CI) [1.25–2.08], P=0.0002]. The association remained significant after matching: HR 1.63 [95% CI (1.22–2.18), P<0.001]. There was only a weak correlation between TV kg−1 IBW and dynamic compliance (r=−0.006, P=0.31) and a weak-to-moderate correlation between TV kg−1 IBW and PIP (r=0.32 P<0.0001).
Conclusions Use of low intraoperative TV with minimal PEEP is associated with an increased risk of 30-day mortality.
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