The Risk of Hypertension after Preoperative
Discontinuation of Angiotensin-Converting Enzyme
Inhibitors or Angiotensin Receptor Antagonists
in Ambulatory and Same-Day Admission Patients
Rebecca S. Twersky, MD, MPH, Vasudha Goel, MD, Preeti Narayan, MD,
and Jeremy Weedon, PhD, MA, BS
Anesth Analg 2014;118:938–44


Discontinuing ACEIs and ARBs in patients on the day of surgery did not result
in a substantively increased incidence of pre- or postoperative HTN compared with patients who
continued these medications on the day of surgery. The results provide an evidentiary basis for
the safety of discontinuing ACEIs and ARBs on the day of surgery without increasing adverse
hemodynamic outcomes.