Dehydration Enhances Pain-Evoked Activation in the Human Brain Compared with Rehydration

Ogino, Yuichi MD, PhD; Kakeda, Takahiro RN, PHN, PhD; Nakamura, Koji MD; Saito, Shigeru MD, PhD

Anesthesia & Analgesia:  June 2014 - Volume 118 - Issue 6 - p 1317–1325

Dehydration brings about increased brain activity related to painful stimuli together with enhanced thirst, whereas rehydration with oral rehydration solution  alleviates thirst and decreases brain activity related to painful stimuli.