Saturday, May 31, 2014

Hypothermic vs normothermic cardiopulmonary bypass on patients with valvular heart disease
Vladimir V Lomivorotov et al

Journal of Cardiothoracic and Vascular Anesthesia
Volume 28, Issue 2 , Pages 295-300, April 2014

Prospective randomized study.
140 patients who had valvular heart disease, with/without coronary artery disease, surgically treated under CPB.

 Normothermic CPB in patients with valvular heart disease was as effective as hypothermic perfusion in terms of myocardial protection after the surgery assessed by cTnI release.
Ventilation time was significantly lower in the hypothermic group
Perioperative dexmedetomidine improves mortality in patients undergoing coronary artery bypass surgery
Fuhai Ji et al

Journal of Cardiothoracic and Vascular Anesthesia
Volume 28, Issue 2 , Pages 267-273, April 2014

Retrospective investigation.
Perioperative dexmedetomidine was used as an intravenous infusion (0.24 to 0.6 µg/kg/hour) initiated after cardiopulmonary bypass and continued for less than 24 hours postoperatively in the intensive care unit.
Dexmedetomidine infusion during CABG surgery was more likely to achieve improved in-hospital, 30-day, and 1-year survival rates, and a significantly lower incidence of delirium.
Effect of adding statins before surgery on mortality and major morbidity : a meta analysis
Joanne Guay et al

 Journal of Cardiothoracic and Vascular Anesthesia
Volume 28, Issue 2 , Pages 255-266, April 2014

 A search for all randomized controlled trials ,adult patients undergoing any type of procedure.
The search produced 29 trials.
Statins reduced the 0-30 days’ risk of myocardial infarction: risk ratio (RR) 0.48 (95%CI 0.38, 0.61); I-square 13.2%; p<0.001; number needed-to-treat 17 (14, 24)
There were no statistical differences at 0-30 days for stroke , acute renal insufficiency or reoperation. There was a trend for a reduced mortality at 1 year.

Thursday, May 29, 2014





Time to administration of epinephrine and outcome after in hospital cardiac arrest with non shockable rhytms:retrospective analysis of large in - hospital data registry




Michael W Donnino et al

BMJ 2014;348:g3028


In patients with non-shockable cardiac arrest in hospital, earlier administration of epinephrine is associated with a higher probability of return of spontaneous circulation, survival in hospital, and neurologically intact survival.






Dose requirements or remifentanil for intubation in non paralized chinese children


Hua-Cheng Liu  et al

Pediatric Anesthesia


Volume 24, Issue 5, pages 505–509, May 2014


When used in combination with 2.5 mg·kg−1 of intravenous propofol, ED50 and ED95 of remifentanil for adequate intubation in nonparalyzed children were lower than previously reported, at 2.30 and 2.75 μg·kg−1, respectively.