Procalcitonin as a predictor of sepsis and outcome in severe trauma patients: a prospective study.

Rajkumari N, Mathur P, Sharma S, Gupta B, Bhoi S, Misra MC

J Lab Physicians. 2013 Jul;5(2):100-8.

Patients with high initial PCT levels (>2 ng/ml) in severe trauma cases had poor outcomes and risk of developing complications. Its correlation with severe outcomes was better marked as compared with CRP and ESR levels. The difference in PCT levels between days 1 and 4 in group two patients was statistically significant (P = 0.006) but were not statistically significant for CRP (P = 0.646) and ESR (P = 0.935). The study also shows that PCT levels fall in response to appropriate antimicrobial treatment.