Thursday, May 15, 2014

Patient Blood Management in Elective Total Hip- and Knee-replacement Surgery (Part 2): A Randomized Controlled Trial on Blood Salvage as Transfusion Alternative Using a Restrictive Transfusion Policy in Patients with a Preoperative Hemoglobin above 13 g/dl

So-Osman, Cynthia M.D., Ph.D., M.Sc.; Nelissen, Rob G. H. H. M.D., Ph.D.; Koopman-van Gemert, Ankie W. M. M. M.D., Ph.D.; Kluyver, Ewoud M.D.; Pöll, Ruud G. M.D., Ph.D.; Onstenk, Ron M.D.; Van Hilten, Joost A. Ph.D.; Jansen-Werkhoven, Thekla M. Ph.D.; van den Hout, Wilbert B. Ph.D.; Brand, Ronald Ph.D.; Brand, Anneke M.D., Ph.D.
 In this prospective randomized controlled trial including 1,759 patients with a preoperative hemoglobin level greater than 13 g/dl (and therefore ineligible for erythropoietin) undergoing hip or knee arthroplasty, autologous intra- and postoperative blood salvage devices were not effective as transfusion alternatives. The use of these devices did not reduce erythrocyte use and increased costs.

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