Nonsteroidal anti-inflammatory drugs’ impact on nonunion and infection rates in long-bone fractures
Jeffcoach, David R. MD; Sams, Valerie G. MD; Lawson, Christy M. MD; Enderson, Blaine L. MD, MBA; Smith, Scott T. MD; Kline, Heather PA-C; Barlow, Patrick B. BA; Wylie, Douglas R. PharmD; Krumenacker, Laura A. PharmD; McMillen, James C. PharmD; Pyda, Jordan BS; Daley, Brian J. MD, MBA ; University of Tennessee Medical Center, Department of Surgery
Journal of Trauma and Acute Care Surgery:
Long bone fracture patients who received NSAIDs in the postoperative period were twice as likely and smokers more than three times likely to suffer complications such as nonunion/malunion or infection. They recommend avoiding NSAID in traumatic long bone fractures.