Nonsteroidal anti-inflammatory
drugs’ impact on nonunion and infection rates in long-bone fractures
Jeffcoach, David R. MD; Sams,
Valerie G. MD; Lawson, Christy M. MD; Enderson, Blaine L. MD, MBA; Smith, Scott
T. MD; Kline, Heather PA-C; Barlow, Patrick B. BA; Wylie, Douglas R. PharmD;
Krumenacker, Laura A. PharmD; McMillen, James C. PharmD; Pyda, Jordan BS;
Daley, Brian J. MD, MBA ; University of Tennessee Medical Center, Department of
Surgery
Journal
of Trauma and Acute Care Surgery:
Long
bone fracture patients who received
NSAIDs in the postoperative period were twice as likely and smokers more than
three times likely to suffer complications such as nonunion/malunion or
infection. They recommend avoiding NSAID in traumatic long bone fractures.
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